Redefining Histological Cell Counts Using a Standardized Method: The Leuven Intestinal Counting Protocol.

Matthias CeulemansPauline HuygheGert De HertoghRaquel CameronJolien ScholGrace L BurnsSimon KeelyLucas WautersJan TackNicholas J TalleyTim Vanuytsel

Published in: Clinical and translational gastroenterology (2024)

We developed and validated a standardized approach to duodenal histological cell quantification, generalizable to various mucosal cell types. Implementation of software-based quantification identified 400 eosinophils/mm 2 and 700 mast cells/mm 2 as thresholds for abnormal duodenal infiltration.

Keyphrases

single cell
cell therapy
healthcare
randomized controlled trial
primary care
stem cells
peripheral blood
quality improvement