TLR-2, TLR-4 and MyD88 genes expression in renal transplant acute and chronic rejections.
Mohammad Hossein SharbafiSara AssadiaslFatemeh Pour-Reza-GholiSaeed BarzegariPeyman Mohammadi TorbatiShiva SamavatMohammad Hossein NicknamAli Akbar AmirzargarPublished in: International journal of immunogenetics (2019)
These data showed that MyD88 gene upregulation in renal tissue could have diagnostic value and increased level of TLR4 mRNA in PBMCs could be suggestive of cell-mediated rejections. Therefore, monitoring the expression level of inflammatory signalling genes might be useful in predicting allograft rejection.
Keyphrases
- toll like receptor
- poor prognosis
- inflammatory response
- genome wide
- genome wide identification
- immune response
- nuclear factor
- binding protein
- long non coding rna
- liver failure
- oxidative stress
- single cell
- drug induced
- cell proliferation
- cell therapy
- copy number
- genome wide analysis
- electronic health record
- respiratory failure
- machine learning
- big data
- stem cells
- mesenchymal stem cells
- kidney transplantation