Blood pressure variability and cognitive decline: A post hoc analysis of the SPRINT MIND trial.

Published in: American journal of hypertension (2022)

Elevated BPV remains a risk for cognitive decline despite strictly controlled BP levels, in the standard treatment group. Specific declines were observed in processing speed and executive function, domains often impacted by cerebrovascular disease and may underpin risk for dementia and cerebrovascular disease associated with BPV.

Keyphrases

cognitive decline
mild cognitive impairment
blood pressure
clinical trial
randomized controlled trial
study protocol
phase iii
skeletal muscle
metabolic syndrome
replacement therapy
open label