Betaine promotes osteogenic differentiation in immortalized human dental pulp-derived cells.

Chatvadee KornsuthisoponDusit NantanapiboonSunisa RochanavibhataNunthawan NowwaroteWorachat NamangkalakulThanaphum Osathanon

Published in: BDJ open (2022)

ihDPs showed superior proliferation ability and a longer life span, which could serve as a promising cell for regenerative dentistry. BET promoted odonto/osteogenic differentiation via intracellular calcium regulation.

Keyphrases

mesenchymal stem cells
cell therapy
bone marrow
induced apoptosis
endothelial cells
stem cells
cell cycle arrest
signaling pathway
induced pluripotent stem cells
endoplasmic reticulum stress
cell death
pluripotent stem cells
tissue engineering