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Optimizing large-scale autologous human keratinocyte sheets for major burns-Toward an animal-free production and a more accessible clinical application.

Laura FreseSalim Elias DarwicheMyrna Elisabeth GunningSimon Philipp HoerstrupBrigitte von RechenbergPietro GiovanoliMaurizio Calcagni
Published in: Health science reports (2022)
This study demonstrated that animal-free components could be used successfully to reduce the risk profile of large-scale autologous keratinocyte sheet production, and thereby increase clinical accessibility.
Keyphrases
  • bone marrow
  • endothelial cells
  • cell therapy
  • platelet rich plasma
  • induced pluripotent stem cells
  • pluripotent stem cells
  • mesenchymal stem cells