Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study.

Filippo BaldacciSimone ListaMaria Laura MancaPatrizia A ChiesaEnrica CavedoPablo LemercierHenrik ZetterbergKaj BlennowMarie-Odile HabertMarie Claude PotierBruno DuboisAndrea VergalloHarald Hampelnull nullnull null

Published in: Alzheimer's research & therapy (2020)

We find that plasma NFL and t-Tau longitudinal trajectories are affected by age and female sex, respectively, in SMC individuals. Exploring the influence of biological variables on AD biomarkers is crucial for their clinical validation in blood.

Keyphrases

depressive symptoms
cerebrospinal fluid
working memory
cross sectional
physical activity