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Successful orthotopic uterine allotransplantation in a rabbit model using aorta and cava anastomoses: a short-term viability study.

Yu LiuYing ZhangYan DingJunwei LiQunye TangXuyin ZhangKe-Qin Hua
Published in: Archives of gynecology and obstetrics (2019)
Aorta and cava anastomoses can be used to ensure a viable transplanted uterus by reconstructing an adequate blood supply to the transplanted uterine graft in a rabbit model. We have demonstrated the feasibility of tacrolimus monotherapy in suppressing the rejection of an allotransplanted uterus in a rabbit model. However, UTx in a rabbit model seems difficult to achieve long-term survival.
Keyphrases
  • aortic valve
  • pulmonary artery
  • signaling pathway
  • combination therapy
  • randomized controlled trial
  • clinical trial
  • pulmonary arterial hypertension