Actin-related protein 2/3 complex subunit 2-enriched extracellular vesicles drive liver cancer metastasis.

Piaorong MeiSze Keong TeySamuel Wan Ki WongTung Him NgXiaowen MaoCherlie Lot Sum YeungYi XuLiang YuQianhua HuangPeihua CaoJudy Wai Ping YamYi Gao

Published in: Hepatology international (2022)

This study reveals previously unreported expression and function of ARPC2 in EVs. EVs with highly expressed ARPC2 enhance cancer cell growth and metastasis. ARPC2 may provide a prospective target for the novel treatment of HCC patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
poor prognosis
chronic kidney disease
prognostic factors
peritoneal dialysis
binding protein