53BP1 expression and immunoscore are associated with the efficacy of neoadjuvant chemoradiotherapy for rectal cancer.

Ai HuangYong XiaoChunfen PengTao LiuZhenyu LinQin YangTao ZhangJun LiuHong Ma

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2019)

The pretreatment levels of 53BP1 and the immunoscore based on CD3+/CD8+ T cell infiltration density in tumor tissues are effective predictors for the CRT response, and 53BP1 has a more pronounced impact on prognosis.

Keyphrases

rectal cancer
locally advanced
poor prognosis
gene expression
cardiac resynchronization therapy
heart failure
lymph node
long non coding rna
left ventricular