Commentary on Cochrane review: "Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder".
Stephane BorentainPooja DesaiDong-Jing FuLi Nancy ChenRosanne LaneMaju MathewsCarla M CanusoPublished in: Journal of psychopharmacology (Oxford, England) (2022)
Esketamine improves response, remission, and depressive symptoms as early as 24 h post-first dose among patients with TRD and among patients with MDD and active suicidal ideation with intent.