Netrin-1 and RGMa: Novel Regulators of Atherosclerosis-Related Diseases.

Xiaofan YuanGuanru ShenHongmei XiaoZijie WangYue MaXinyue Qin

Published in: Cardiovascular drugs and therapy (2023)

However, mechanistic studies have generated controversy about the specific role of Netrin-1 in atherosclerosis due to the diversity of its structure, receptors and cell sources, and the actions of RGMa in atherosclerosis have not been reported in previous reviews. Therefore, the current work reviews the evidence for roles of Netrin-1 and RGMa in the initiation and progression of atherosclerosis and discusses potential therapeutic targets in the future.

Keyphrases

cardiovascular disease
single cell
randomized controlled trial
type diabetes
systematic review
drinking water
risk assessment
human health