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Can Molecular Imaging Find a Path to Navigate Evolving Breast Cancer Treatments?

Hannah M LindenDavid A Mankoff
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
FES PET is an FDA-approved imaging biomarker. Like IHC, FES positivity predicts clinical benefit of endocrine therapy. In addition, FES measures the target activity in endocrine agent drug development. A recent study found that whole body tumor heterogeneity of expression predicts clinical benefit, and serial FES monitors ER blockade and post treatment release.
Keyphrases
  • poor prognosis
  • high resolution
  • computed tomography
  • stem cells
  • endoplasmic reticulum
  • combination therapy
  • long non coding rna
  • fluorescence imaging