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Safety and tolerability of intravitreal umedaptanib pegol (anti-FGF2) for neovascular age-related macular degeneration (nAMD): a phase 1, open-label study.

Daniel S PereiraKazumasa AkitaRobert B BhisitkulToshiaki NishihataYusuf AliEmiko NakamuraYoshikazu Nakamura
Published in: Eye (London, England) (2023)
Intravitreal umedaptanib pegol was safe, well tolerated, and demonstrated an indication of bioactivity in participants that have persistent subretinal fluid refractory to the treatment with anti-VEGFs.
Keyphrases
  • age related macular degeneration
  • open label
  • clinical trial
  • phase ii
  • phase iii
  • study protocol
  • randomized controlled trial
  • squamous cell carcinoma
  • combination therapy