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Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

Marta S PalmeirimEveline HürlimannStefanie KnoppBenjamin SpeichVicente BelizarioSerene A JosephMichel T VaillantPiero OlliaroJennifer Keiser
Published in: PLoS neglected tropical diseases (2018)
Our findings suggest a good tolerability and higher efficacy of ivermectin-albendazole against T. trichiura compared to the current standard single-dose albendazole treatment, which supports the use of this co-administration in PC programs. Large-scale definitive randomized controlled trials are required to confirm our results.
Keyphrases
  • data analysis
  • systematic review
  • meta analyses
  • randomized controlled trial
  • public health
  • open label
  • drug administration
  • radiation therapy
  • replacement therapy
  • placebo controlled
  • smoking cessation