Neuropsychological Functioning in Primary Dystonia: Updated and Expanded Multidomain Meta-Analysis.
Stephen L AitaVictor A Del BeneDario A MarottaJasmin H PizerNanako A HawleyLindsay NiccolaiHarrison C WalkerAdam GersteneckerRoy C MartinOlivio J ClayMichael CroweKristen L TriebelBenjamin D HillPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
Dystonia patients consistently demonstrated lower performances on neuropsychological tests versus HCs. Effect sizes were generally moderate in strength, clustering around -0.50 SD units. Within the speed domain, results suggested cognitive slowing beyond effects from motor symptoms. Overall, findings indicate dystonia patients experience multidomain cognitive difficulties, as detected by neuropsychological tests. © 2022 International Parkinson and Movement Disorder Society.