High expression of AlkB homolog 5 suppresses the progression of non-small cell lung cancer by facilitating ferroptosis through m6A demethylation of SLC7A11.
Zhangzhou HuangGen LinYaping HongLihong WengKai ZhuZhangzhou HuangPublished in: Environmental toxicology (2024)
ALKBH5 upregulation downregulates SLC7A11 transcription by decreasing m6A modification, thus promoting NSCLC cell ferroptosis and ultimately repressing NSCLC progression.