Molecular characterization of antimicrobial resistance related genes in E. coli, Salmonella and Klebsiella isolates from broilers in the West Region of Cameroon.
Jude Fonbah LeinyuyInnocent Mbulli AliKarimo OusenuChristopher B TumePublished in: PloS one (2023)
A high carriage of plasmid-mediated genes for ESBL, quinolone, and aminoglycoside resistance was found among the Enterobacteriaceae tested. However, gene carriage was not always correlated with phenotypic expression. This allows us to suggest that assessing genetic determinants of resistance should not be based on AST profile only. Further studies, including assessing the role of chromosomal determinants will shed light on other factors that undermine antimicrobial susceptibility locally.
Keyphrases
- escherichia coli
- antimicrobial resistance
- genome wide
- copy number
- klebsiella pneumoniae
- pseudomonas aeruginosa
- genome wide identification
- poor prognosis
- multidrug resistant
- dna methylation
- acinetobacter baumannii
- heat stress
- gene expression
- genome wide analysis
- drug resistant
- cystic fibrosis
- long non coding rna
- bioinformatics analysis