Factors detrimental to work productivity and daily activities in systemic lupus erythematosus patients - Analysis of the German LuLa study.
Anna KernderChristina DüsingJutta RichterRalph BrinksRebecca Fischer-BetzBorgi Winkler-RohlfingMartin AringerMatthias SchneiderGamal ChehabPublished in: Lupus (2021)
In employed patients with SLE, impaired work productivity and impaired daily activities were frequently reported. Fatigue, pain, disease activity and health-related quality of life demonstrated a detrimental impact, with a synergistic effect of fatigue, disease activity and pain. Hence, both optimized pain management and targeted immunomodulatory therapy are important for preserving active participation in life among patients with fatigue.
Keyphrases
- disease activity
- pain management
- systemic lupus erythematosus
- rheumatoid arthritis
- chronic pain
- rheumatoid arthritis patients
- ankylosing spondylitis
- juvenile idiopathic arthritis
- physical activity
- sleep quality
- end stage renal disease
- ejection fraction
- climate change
- newly diagnosed
- cancer therapy
- peritoneal dialysis
- spinal cord
- mesenchymal stem cells