Pain, depressive symptoms, and health-related quality of life among survivors of pediatric hematopoietic stem cell transplant.

Kimberly L Klages Marie L ChardonSarah N DrakeKasiani C MyersCaroline F MorrisonAhna L H Pai

Published in: Pediatric blood & cancer (2022)

Greater pain intensity was associated directly with increased depressive symptoms and indirectly with HRQoL through depressive symptoms. Results of this study suggest that multitargeted cognitive behavioral interventions that address pain and depressive symptoms may improve HRQoL ratings in survivors of pediatric HCT.

Keyphrases

depressive symptoms
chronic pain
social support
pain management
neuropathic pain
hematopoietic stem cell
sleep quality
young adults
physical activity
spinal cord injury
spinal cord
high intensity
cell death
cell cycle arrest