Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis.

Shaimaa Ali Ali RadwanWalaa H El-MaadawyAliaa Nabil ElMeshadRaguia Aly ShoukriCarol Yousry

Published in: Pharmaceutical research (2020)

These findings emphasize the promising application of RMLNC as a delivery system in hepatic fibrosis treatment, where successful delivery of GA into aHSCs was ensured via increased cellular uptake and antifibrotic activities.

Keyphrases

induced apoptosis
pet ct
drug delivery
cell cycle arrest
cancer therapy
fatty acid
liver fibrosis
signaling pathway
combination therapy
endoplasmic reticulum stress
pi k akt