A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro.
Philipp SchlaermannBenjamin ToelleHilmar BergerSven C SchmidtMatthias GlanemannJürgen OrdemannSina BartfeldHans J MollenkopfThomas F MeyerPublished in: Gut (2014)
A robust and quasi-immortal 3D organoid model has been established, which is considered instrumental for future research aimed to understand the underlying mechanisms of infection, mucosal immunity and cancer of the human stomach.