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Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches.

Mohamed S NafieAhmed I KhodairHebat Allah Y HassanNoha M Abd El-FadealHanin A BogariSameh S ElhadySafwat A Ahmed
Published in: Molecules (Basel, Switzerland) (2021)
has a promising anti-cancer activity through activating antioxidant levels (CAT, SOD and GSH) and ameliorating hematological, biochemical, and histopathological findings.
Keyphrases
  • oxidative stress
  • anti inflammatory
  • signaling pathway
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • amyotrophic lateral sclerosis