Mohamed S Nafie

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 97

Top Venues

Molecules (Basel, Switzerland)

ACS omega

Pharmaceuticals (Basel, Switzerland)

RSC advances

Suez Canal University

Suez Canal University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Suez Canal University Aug 28 2018

Egypt

Lecturer of Biochemistry and Drug Design :: Chemistry

Suez Canal University Oct 26 2011 - Aug 27 2018

Egypt

Assistant teaching staff :: Science/ Chemsirty

Education History

Suez Canal University Dec 27 2015 - Jul 26 2018

Egypt

PHD :: Science/ Chemistry

Università di Pisa Sep 21 2017 - Jul 10 2018

Italy

PHD :: Pharmacy

Publications

Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Sahar Ahmed El-Shatoury
Metabolite profiling and in-silico studies show multiple effects of insecticidal actinobacterium on Spodoptera littoralis. Scientific reports 14 (1) (2024)
Donia El Sayed, Samir Mohamed El Rayes, Hamdy A Soliman, Imad Eddin AlBalaa, Mansour S Alturki, Abdulaziz Hassan Al Khzem, Mohammed Abdullah Alsharif, Mohamed S Nafie
Synthesis of novel phthalazine-based derivatives with potent cytotoxicity against HCT-116 cells through apoptosis and VEGFR2 inhibition. RSC advances 14 (19) (2024)
Eman S Tantawy, Mohamed S Nafie, Hesham A Morsy, Hassan A El-Sayed, Ahmed H Moustafa, Samar M Mohammed
Synthesis of novel bioactive pyrido[2,3- d ]pyrimidine derivatives with potent cytotoxicity through apoptosis as PIM-1 kinase inhibitors. RSC advances 14 (16) (2024)
Doaa M Mohamed, Nabila A Kheder, Marwa Sharaky, Mohamed S Nafie, Kamal M Dawood, Ashraf A Abbas
Synthesis of novel piperazine-based bis(thiazole)(1,3,4-thiadiazole) hybrids as anti-cancer agents through caspase-dependent apoptosis. RSC advances 14 (34) (2024)
Fawzia F Albelwi, Mohamed S Nafie, Nader R Albujuq, Wafa Hourani, Ateyatallah Aljuhani, Khaled M Darwish, Mohamed M Tawfik, Nadjet Rezki, Mohamed Reda Aouad
Design and synthesis of chromene-1,2,3-triazole benzene sulfonamide hybrids as potent carbonic anhydrase-IX inhibitors against prostate cancer. RSC medicinal chemistry 15 (7) (2024)
Mohamed S Nafie, Shaima H Kahwash, Magdy M Youssef, Kamal M Dawood
Recent advances on quinoxalines as target-oriented chemotherapeutic anticancer agents through apoptosis. Archiv der Pharmazie (2024)
Ahmed M Badawy, Enas E Eltamany, Rodina M Hussien, Osama G Mohamed, Mayada M El-Ayouty, Mohamed S Nafie, Ashootosh Tripathi, Safwat A Ahmed
Cornulacin: a new isoflavone from Cornulaca monacantha and its isolation, structure elucidation and cytotoxicity through EGFR-mediated apoptosis. RSC medicinal chemistry (2024)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Sahar Ahmed El-Shatoury
Metabolite profiling and in-silico studies show multiple effects of insecticidal actinobacterium on Spodoptera littoralis. Scientific reports 14 (1) (2024)
Doaa M Mohamed, Nabila A Kheder, Marwa Sharaky, Mohamed S Nafie, Kamal M Dawood, Ashraf A Abbas
Synthesis of novel piperazine-based bis(thiazole)(1,3,4-thiadiazole) hybrids as anti-cancer agents through caspase-dependent apoptosis. RSC advances 14 (34) (2024)
Mohammad Shahidul Islam, Refaah M Al-Jassas, Abdullah Mohammed Al-Majid, Matti Haukka, Mohamed S Nafie, Marwa M Abu-Serie, Mohamed Teleb, Amira F El-Yazbi, Abdul Majeed Abdullah Alayyaf, Assem Barakat, Marwa M Shaaban
Exploiting spirooxindoles for dual DNA targeting/CDK2 inhibition and simultaneous mitigation of oxidative stress towards selective NSCLC therapy; synthesis, evaluation, and molecular modelling studies. RSC medicinal chemistry 15 (8) (2024)
Yasmine M Abdel Aziz, Mohamed S Nafie, Pierre A Hanna, Sherif Ramadan, Assem Barakat, Marwa Elewa
Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 Inhibitors with Anti-Platelet Aggregation Activity. Pharmaceuticals (Basel, Switzerland) 17 (6) (2024)
Mohamed S Nafie, Shaima H Kahwash, Magdy M Youssef, Kamal M Dawood
Recent advances on quinoxalines as target-oriented chemotherapeutic anticancer agents through apoptosis. Archiv der Pharmazie 357 (9) (2024)
Donia El Sayed, Samir Mohamed El Rayes, Hamdy A Soliman, Imad Eddin AlBalaa, Mansour S Alturki, Abdulaziz Hassan Al Khzem, Mohammed Abdullah Alsharif, Mohamed S Nafie
Synthesis of novel phthalazine-based derivatives with potent cytotoxicity against HCT-116 cells through apoptosis and VEGFR2 inhibition. RSC advances 14 (19) (2024)
Yasmine M Abdel Aziz, Mohamed S Nafie, Pierre A Hanna, Sherif Ramadan, Assem Barakat, Marwa Elewa
Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 Inhibitors with Anti-Platelet Aggregation Activity. Pharmaceuticals (Basel, Switzerland) 17 (6) (2024)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Sahar Ahmed El-Shatoury
Metabolite profiling and in-silico studies show multiple effects of insecticidal actinobacterium on Spodoptera littoralis. Scientific reports 14 (1) (2024)
Eman S Tantawy, Mohamed S Nafie, Hesham A Morsy, Hassan A El-Sayed, Ahmed H Moustafa, Samar M Mohammed
Synthesis of novel bioactive pyrido[2,3- d ]pyrimidine derivatives with potent cytotoxicity through apoptosis as PIM-1 kinase inhibitors. RSC advances 14 (16) (2024)
Fawzia F Albelwi, Mohamed S Nafie, Nader R Albujuq, Wafa Hourani, Ateyatallah Aljuhani, Khaled M Darwish, Mohamed M Tawfik, Nadjet Rezki, Mohamed Reda Aouad
Design and synthesis of chromene-1,2,3-triazole benzene sulfonamide hybrids as potent carbonic anhydrase-IX inhibitors against prostate cancer. RSC medicinal chemistry 15 (7) (2024)
Samir Mohamed El Rayes, Ibrahim A I Ali, Walid Fathalla, Mohamed A Ghanem, Afaf H El-Sagheer, Mohamed S Nafie
Synthesis of N -Alkyl-3-[2-oxoquinolin-1(2 H )-yl]propanoic Acid Derivatives and Related Compounds: Cytotoxicity and EGFR Inhibition of Some Propanamide Derivatives. ACS omega 9 (30) (2024)
Marola Paula Fawzy, Hatem A F M Hassan, Nada K Sedky, Mohamed S Nafie, Rana A Youness, Sherif Ashraf Fahmy
Revolutionizing cancer therapy: nanoformulation of miRNA-34 - enhancing delivery and efficacy for various cancer immunotherapies: a review. Nanoscale advances (2024)
Mayada E G Elsakka, Mohamed M Tawfik, Lamiaa A A Barakat, Mohamed S Nafie
A quinoxaline-based derivative exhibited potent and selective anticancer activity with apoptosis induction in PC-3 cells through Topo II inhibition. Journal of biomolecular structure & dynamics (2024)
Heba A Elsebaie, Mohamed S Nafie, Haytham O Tawfik, Amany Belal, Mohammed M Ghoneim, Ahmad J Obaidullah, Salwa Shaaban, Abdelmoneim A Ayed, Mohamed El-Naggar, Ahmed B M Mehany, Moataz A Shaldam
Discovery of new 1,3-diphenylurea appended aryl pyridine derivatives as apoptosis inducers through c-MET and VEGFR-2 inhibition: design, synthesis, in vivo and in silico studies. RSC medicinal chemistry 15 (7) (2024)
Ahmed M Badawy, Enas E Eltamany, Rodina M Hussien, Osama G Mohamed, Mayada M El-Ayouty, Mohamed S Nafie, Ashootosh Tripathi, Safwat A Ahmed
Cornulacin: a new isoflavone from Cornulaca monacantha and its isolation, structure elucidation and cytotoxicity through EGFR-mediated apoptosis. RSC medicinal chemistry (2024)
Mohammad Shahidul Islam, Refaah M Al-Jassas, Abdullah Mohammed Al-Majid, Matti Haukka, Mohamed S Nafie, Marwa M Abu-Serie, Mohamed Teleb, Amira F El-Yazbi, Abdul Majeed Abdullah Alayyaf, Assem Barakat, Marwa M Shaaban
Exploiting spirooxindoles for dual DNA targeting/CDK2 inhibition and simultaneous mitigation of oxidative stress towards selective NSCLC therapy; synthesis, evaluation, and molecular modelling studies. RSC medicinal chemistry 15 (8) (2024)
Mohamed S Nafie, Mohab A Ali, Magdy M Youssef
N-allyl quinoxaline derivative exhibited potent and selective cytotoxicity through EGFR/VEGFR-mediated apoptosis: In vitro and in vivo studies. Journal of biochemical and molecular toxicology 38 (4) (2024)
Samir Mohamed El Rayes, Ibrahim A I Ali, Walid Fathalla, Mohamed A Ghanem, Afaf H El-Sagheer, Mohamed S Nafie
Synthesis of N -Alkyl-3-[2-oxoquinolin-1(2 H )-yl]propanoic Acid Derivatives and Related Compounds: Cytotoxicity and EGFR Inhibition of Some Propanamide Derivatives. ACS omega 9 (30) (2024)
Heba A Elsebaie, Mohamed S Nafie, Haytham O Tawfik, Amany Belal, Mohammed M Ghoneim, Ahmad J Obaidullah, Salwa Shaaban, Abdelmoneim A Ayed, Mohamed El-Naggar, Ahmed B M Mehany, Moataz A Shaldam
Discovery of new 1,3-diphenylurea appended aryl pyridine derivatives as apoptosis inducers through c-MET and VEGFR-2 inhibition: design, synthesis, in vivo and in silico studies. RSC medicinal chemistry 15 (7) (2024)
Nermeen A Eltahawy, Asmaa I Ali, Salma A Ibrahim, Mohamed S Nafie, Amal Mohammed Sindi, Hanaa Alkharobi, Ahmad J Almalki, Jihan M Badr, Sameh S Elhady, Reda F A Abdelhameed
Analysis of Marrubiin in Marrubium alysson L. Extract Using Advanced HPTLC: Chemical Profiling, Acetylcholinesterase Inhibitory Activity, and Molecular Docking. Metabolites 14 (1) (2023)
Ranza Elrayess, Mohamed Saleh Elgawish, Mohamed S Nafie, Nagat Ghareb, Asmaa S A Yassen
2-Phenylquinazolin-4(3H)-one scaffold as newly designed, synthesized VEGFR-2 allosteric inhibitors with potent cytotoxicity through apoptosis. Archiv der Pharmazie (2023)
Eid E Salama, Mohamed F Youssef, Abouelmagd A, Ahmed T A Boraei, Mohamed S Nafie, Matti Haukka, Assem Barakat, Ahmed A M Sarhan
Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (12) (2023)
Ahmed I Khodair, Fatimah M Alzahrani, Mohamed K Awad, Siham A Al-Issa, Ghaferah H Al-Hazmi, Mohamed S Nafie
Design, Synthesis, Computational Investigations, and Antitumor Evaluation of N -Rhodanine Glycosides Derivatives as Potent DNA Intercalation and Topo II Inhibition against Cancer Cells. ACS omega 8 (14) (2023)
Dalia H Soliman, Mohamed S Nafie
Design, synthesis, and docking studies of novel pyrazole-based scaffolds and their evaluation as VEGFR2 inhibitors in the treatment of prostate cancer. RSC advances 13 (30) (2023)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Amro Mohamed Said Hanora, Sahar Ahmed El-Shatoury
Endophytic actinobacteria from wild medicinal plants are a natural source of insecticide to control the African cotton leafworm (Spodoptera littoralis). AMB Express 13 (1) (2023)
Refaah Mousa Al-Jassas, Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Mohamed S Nafie, Matti Haukka, A F M Motiur Rahman, Abdul Majeed Abdullah Alayyaf, Assem Barakat
Synthesis and SARs study of novel spiro-oxindoles as potent antiproliferative agents with CDK-2 inhibitory activities. Archiv der Pharmazie (2023)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Amro Mohamed Said Hanora, Sahar Ahmed El-Shatoury
Endophytic actinobacteria from wild medicinal plants are a natural source of insecticide to control the African cotton leafworm (Spodoptera littoralis). AMB Express 13 (1) (2023)
Eid E Salama, Mohamed F Youssef, Abouelmagd A, Ahmed T A Boraei, Mohamed S Nafie, Matti Haukka, Assem Barakat, Ahmed A M Sarhan
Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (12) (2023)
Enas E Eltamany, Mohamed S Nafie, Dina M Hal, Maged S Abdel-Kader, Abdelghafar Mohamed Abu-Elsaoud, Safwat A Ahmed, Amany K Ibrahim, Jihan M Badr, Reda F A Abdelhameed
A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition. ACS omega 8 (33) (2023)
Mohammed Farrag El-Behairy, Walaa Hamada Abd-Allah, Mohamed M Khalifa, Mohamed S Nafie, Mohamed A Saleh, Mohammed S Abdel-Maksoud, Tarfah Al-Warhi, Wagdy M Eldehna, Ahmed Ali Al-Karmalawy
Design and synthesis of novel rigid dibenzo[ b,f ]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Nermeen A Eltahawy, Asmaa I Ali, Salma A Ibrahim, Mohamed S Nafie, Amal Mohammed Sindi, Hanaa Alkharobi, Ahmad J Almalki, Jihan M Badr, Sameh S Elhady, Reda F A Abdelhameed
Analysis of Marrubiin in Marrubium alysson L. Extract Using Advanced HPTLC: Chemical Profiling, Acetylcholinesterase Inhibitory Activity, and Molecular Docking. Metabolites 14 (1) (2023)
Mai M Sayed, Zohour I Nabil, Nahla S El-Shenawy, Rasha A Al-Eisa, Mohamed S Nafie
In Vitro and In Vivo Effects of Synthesis Novel Phenoxyacetamide Derivatives as Potent Apoptotic Inducer against HepG2 Cells through PARP-1 Inhibition. Pharmaceuticals (Basel, Switzerland) 16 (11) (2023)
Shrouk M Shaban, Elsayed H Eltamany, Ahmed T A Boraei, Mohamed S Nafie, Emad M Gad
Design and Synthesis of Novel Pyridine-Based Compounds as Potential PIM-1 Kinase Inhibitors, Apoptosis, and Autophagy Inducers Targeting MCF-7 Cell Lines: In Vitro and In Vivo Studies. ACS omega 8 (49) (2023)
Mostafa E Salem, Esraa M Mahrous, Eman A Ragab, Mohamed S Nafie, Kamal M Dawood
Synthesis and Anti-Breast Cancer Potency of Mono- and Bis-(pyrazolyl[1,2,4]triazolo[3,4- b ][1,3,4]thiadiazine) Derivatives as EGFR/CDK-2 Target Inhibitors. ACS omega 8 (38) (2023)
Eid E Salama, Mohamed F Youssef, Abouelmagd A, Ahmed T A Boraei, Mohamed S Nafie, Matti Haukka, Assem Barakat, Ahmed A M Sarhan
Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (12) (2023)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Amro Mohamed Said Hanora, Sahar Ahmed El-Shatoury
Endophytic actinobacteria from wild medicinal plants are a natural source of insecticide to control the African cotton leafworm (Spodoptera littoralis). AMB Express 13 (1) (2023)
Nermeen A Eltahawy, Shady A Swidan, Mohamed S Nafie, Abdulaziz S Saeedan, Ali M Nasr, Jihan M Badr, Reda F A Abdelhameed
Silver nanoparticles formulation of Marrubium alysson L. phenolic extract potentiates cytotoxicity through apoptosis with molecular docking study as Bcl-2 inhibitors. Journal of biomolecular structure & dynamics (2023)
Ahmed I Khodair, Fatimah Mohammed Alzahrani, Mohamed K Awad, Siham A Al-Issa, Ghaferah H Al-Hazmi, Mohamed S Nafie
Design, synthesis, molecular modelling and antitumor evaluation of S -glucosylated rhodanines through topo II inhibition and DNA intercalation. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Ahmed I Khodair, Fatimah Mohammed Alzahrani, Mohamed K Awad, Siham A Al-Issa, Ghaferah H Al-Hazmi, Mohamed S Nafie
Design, synthesis, molecular modelling and antitumor evaluation of S -glucosylated rhodanines through topo II inhibition and DNA intercalation. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Mohammed Farrag El-Behairy, Walaa Hamada Abd-Allah, Mohamed M Khalifa, Mohamed S Nafie, Mohamed A Saleh, Mohammed S Abdel-Maksoud, Tarfah Al-Warhi, Wagdy M Eldehna, Ahmed Ali Al-Karmalawy
Design and synthesis of novel rigid dibenzo[ b,f ]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Mohammed Abdalla Hussein, Rita M Borik, Mohamed S Nafie, Heba M Abo-Salem, Sylvia A Boshra, Zahraa N Mohamed
Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors. Molecules (Basel, Switzerland) 28 (16) (2023)
Shrouk M Shaban, Elsayed H Eltamany, Ahmed T A Boraei, Mohamed S Nafie, Emad M Gad
Design and Synthesis of Novel Pyridine-Based Compounds as Potential PIM-1 Kinase Inhibitors, Apoptosis, and Autophagy Inducers Targeting MCF-7 Cell Lines: In Vitro and In Vivo Studies. ACS omega 8 (49) (2023)
Nermeen A Eltahawy, Asmaa I Ali, Salma A Ibrahim, Mohamed S Nafie, Amal Mohammed Sindi, Hanaa Alkharobi, Ahmad J Almalki, Jihan M Badr, Sameh S Elhady, Reda F A Abdelhameed
Analysis of Marrubiin in Marrubium alysson L. Extract Using Advanced HPTLC: Chemical Profiling, Acetylcholinesterase Inhibitory Activity, and Molecular Docking. Metabolites 14 (1) (2023)
Eid E Salama, Mohamed F Youssef, Abouelmagd A, Ahmed T A Boraei, Mohamed S Nafie, Matti Haukka, Assem Barakat, Ahmed A M Sarhan
Discovery of Potent Indolyl-Hydrazones as Kinase Inhibitors for Breast Cancer: Synthesis, X-ray Single-Crystal Analysis, and In Vitro and In Vivo Anti-Cancer Activity Evaluation. Pharmaceuticals (Basel, Switzerland) 16 (12) (2023)
Assem Barakat, Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Matti Haukka, Marwa M Abu-Serie, Luis R Domingo, Sajda Ashraf, Zaheer Ul Haq, Mohamed S Nafie, Mohamed Teleb
New spiro-indeno[1,2- b ]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Sara M Emam, Samir M El Rayes, Ibrahim A I Ali, Hamdy A Soliman, Mohamed S Nafie
Synthesis of phthalazine-based derivatives as selective anti-breast cancer agents through EGFR-mediated apoptosis: in vitro and in silico studies. BMC chemistry 17 (1) (2023)
Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad Ahmad Khedr, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Amro Mohamed Said Hanora, Sahar Ahmed El-Shatoury
Endophytic actinobacteria from wild medicinal plants are a natural source of insecticide to control the African cotton leafworm (Spodoptera littoralis). AMB Express 13 (1) (2023)
Enas E Eltamany, Marwa S Goda, Mohamed S Nafie, Abdelghafar Mohamed Abu-Elsaoud, Rawan H Hareeri, Mohammed M Aldurdunji, Sameh S Elhady, Jihan M Badr, Nermeen A Eltahawy
Comparative Assessment of the Antioxidant and Anticancer Activities of Plicosepalus acacia and Plicosepalus curviflorus : Metabolomic Profiling and In Silico Studies. Antioxidants (Basel, Switzerland) 11 (7) (2022)
Ahmed Ali Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, Ayman Abo Elmaaty, Samar A Antar, Anwar A El-Hamaky, Mohamed A Saleh, Ahmed Elkamhawy, Haytham O Tawfik
Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. Journal of medicinal chemistry 66 (1) (2022)
Elsayed Elgazzar, Mohamed S Nafie, Kareem T Abul-Nasr
New synthetic silver-doped ZnO nanorods trigger cytotoxicity in MCF-7 through apoptosis and antimicrobial activity. Journal of biomolecular structure & dynamics (2022)
Mohamed S Gomaa, Ibrahim A I Ali, Gaber El Enany, El Sayed H El Ashry, Samir Mohamed El Rayes, Walid Fathalla, Abdulghany H A Ahmed, Samar A Abubshait, Haya A Abubshait, Mohamed S Nafie
Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition. Molecules (Basel, Switzerland) 27 (23) (2022)
Reda F A Abdelhameed, Mohamed S Nafie, Dina M Hal, Ali M Nasr, Shady A Swidan, Maged S Abdel-Kader, Amany K Ibrahim, Safwat A Ahmed, Jihan M Badr, Enas E Eltamany
Comparative Cytotoxic Evaluation of Zygophyllum album Root and Aerial Parts of Different Extracts and Their Biosynthesized Silver Nanoparticles on Lung A549 and Prostate PC-3 Cancer Cell Lines. Pharmaceuticals (Basel, Switzerland) 15 (11) (2022)
Ahmed Ali Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, Ayman Abo Elmaaty, Samar A Antar, Anwar A El-Hamaky, Mohamed A Saleh, Ahmed Elkamhawy, Haytham O Tawfik
Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. Journal of medicinal chemistry (2022)
Mohamed F Youssef, Mohamed S Nafie, Eid E Salama, Ahmed T A Boraei, Emad M Gad
Synthesis of New Bioactive Indolyl-1,2,4-Triazole Hybrids As Dual Inhibitors for EGFR/PARP-1 Targeting Breast and Liver Cancer Cells. ACS omega 7 (49) (2022)
Nourhan A Magdy, Mohamed S Nafie, Mohamed S El-Naggar, Mohamed A Abu El-Regal, Ahmed Z Abdel Azeiz, Mohamed A Abdel-Rahman, Mokhtar El-Zawahry
Cytotoxicity and apoptosis induction of the marine Conus flavidus venom in HepG2 cancer cell line. Journal of biomolecular structure & dynamics (2022)
Mariam M Fakhry, Kazem Mahmoud, Mohamed S Nafie, Ahmad O Noor, Rawan H Hareeri, Ismail Salama, Safaa M Kishk
Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells. Pharmaceuticals (Basel, Switzerland) 15 (10) (2022)
Ahmed Ali Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, Ayman Abo Elmaaty, Samar A Antar, Anwar A El-Hamaky, Mohamed A Saleh, Ahmed Elkamhawy, Haytham O Tawfik
Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. Journal of medicinal chemistry 66 (1) (2022)
Amgad I M Khedr, Marwa S Goda, Abdelaziz F S Farrag, Ali M Nasr, Shady A Swidan, Mohamed S Nafie, Maged S Abdel-Kader, Jihan M Badr, Reda F A Abdelhameed
Silver Nanoparticles Formulation of Flower Head's Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation. Molecules (Basel, Switzerland) 27 (19) (2022)
Samir Mohamed El Rayes, Gaber El Enany, Ibrahim A I Ali, Wessam Ibrahim, Mohamed S Nafie
Synthesis of Novel Phthalazinedione-Based Derivatives with Promising Cytotoxic, Anti-bacterial, and Molecular Docking Studies as VEGFR2 Inhibitors. ACS omega 7 (30) (2022)
Mohamed F Youssef, Mohamed S Nafie, Eid E Salama, Ahmed T A Boraei, Emad M Gad
Synthesis of New Bioactive Indolyl-1,2,4-Triazole Hybrids As Dual Inhibitors for EGFR/PARP-1 Targeting Breast and Liver Cancer Cells. ACS omega 7 (49) (2022)
Amgad I M Khedr, Abdelaziz F S Farrag, Ali M Nasr, Shady A Swidan, Mohamed S Nafie, Maged S Abdel-Kader, Marwa S Goda, Jihan M Badr, Reda F A Abdelhameed
Comparative Estimation of the Cytotoxic Activity of Different Parts of Cynara scolymus L.: Crude Extracts versus Green Synthesized Silver Nanoparticles with Apoptotic Investigation. Pharmaceutics 14 (10) (2022)
Mohamed S Gomaa, Ibrahim A I Ali, Gaber El Enany, El Sayed H El Ashry, Samir Mohamed El Rayes, Walid Fathalla, Abdulghany H A Ahmed, Samar A Abubshait, Haya A Abubshait, Mohamed S Nafie
Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition. Molecules (Basel, Switzerland) 27 (23) (2022)
Mohamed S Gomaa, Ibrahim A I Ali, Gaber El Enany, El Sayed H El Ashry, Samir Mohamed El Rayes, Walid Fathalla, Abdulghany H A Ahmed, Samar A Abubshait, Haya A Abubshait, Mohamed S Nafie
Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition. Molecules (Basel, Switzerland) 27 (23) (2022)
Mohamed S Gomaa, Ibrahim A I Ali, Gaber El Enany, El Sayed H El Ashry, Samir Mohamed El Rayes, Walid Fathalla, Abdulghany H A Ahmed, Samar A Abubshait, Haya A Abubshait, Mohamed S Nafie
Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition. Molecules (Basel, Switzerland) 27 (23) (2022)
Ihab Shawish, Assem Barakat, Ali K Aldalbahi, Walhan Mohammad Alshaer, Fadwa Daoud, Dana A Alqudah, Mazhar Salim Al Zoubi, Ma'mon M Hatmal, Mohamed S Nafie, Matti Haukka, Anamika Sharma, Beatriz G de la Torre, Fernando Albericio, Matti Haukka
Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s -Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades. Pharmaceutics 14 (8) (2022)
Mohamed M Khalifa, Ahmed A Al-Karmalawy, Eslam B Elkaeed, Mohamed S Nafie, Mohamed A Tantawy, Ibrahim H Eissa, Hazem A Mahdy
Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Ahmed Ali Al-Karmalawy, Mohamed S Nafie, Moataz A Shaldam, Ayman Abo Elmaaty, Samar A Antar, Anwar A El-Hamaky, Mohamed A Saleh, Ahmed Elkamhawy, Haytham O Tawfik
Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. Journal of medicinal chemistry 66 (1) (2022)
Ihab Shawish, Assem Barakat, Ali K Aldalbahi, Azizah M Malebari, Mohamed S Nafie, Adnan A Bekhit, Amgad Albohy, Alamgir Khan, Zaheer Ul-Haq, Matti Haukka, Beatriz G de la Torre, Fernando Albericio, Matti Haukka
Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)- s -triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades. ACS omega 7 (28) (2022)
Safaa M Kishk, Enas E Eltamany, Mohamed S Nafie, Roaa M Khinkar, Rawan H Hareeri, Sameh S Elhady, Asmaa S A Yassen
Design and Synthesis of Coumarin Derivatives as Cytotoxic Agents through PI3K/AKT Signaling Pathway Inhibition in HL60 and HepG2 Cancer Cells. Molecules (Basel, Switzerland) 27 (19) (2022)
Marwa S Goda, Sameh S Elhady, Mohamed S Nafie, Hanin A Bogari, Raina T Malatani, Rawan H Hareeri, Jihan M Badr, Marwa S Donia
Phragmanthera austroarabica A.G.Mill. and J.A.Nyberg Triggers Apoptosis in MDA-MB-231 Cells In Vitro and In Vivo Assays: Simultaneous Determination of Selected Constituents. Metabolites 12 (10) (2022)
Fatma M Thabet, Kamal M Dawood, Eman A Ragab, Mohamed S Nafie, Ashraf A Abbas
Design and synthesis of new bis(1,2,4-triazolo[3,4- b ][1,3,4]thiadiazines) and bis((quinoxalin-2-yl)phenoxy)alkanes as anti-breast cancer agents through dual PARP-1 and EGFR targets inhibition. RSC advances 12 (36) (2022)
Sameh S Elhady, Elsayed A Ibrahim, Marwa S Goda, Mohamed S Nafie, Hanan Samir, Reem M Diri, Abdulrahman M Alahdal, Ama Kyeraa Thomford, Alaa El Gindy, Ghada M Hadad, Jihan M Badr, Reda F A Abdelhameed
GC-MS/MS Quantification of EGFR Inhibitors, β -Sitosterol, Betulinic Acid, (+) Eriodictyol, (+) Epipinoresinol, and Secoisolariciresinol, in Crude Extract and Ethyl Acetate Fraction of Thonningia sanguinea . Molecules (Basel, Switzerland) 27 (13) (2022)
Reda F A Abdelhameed, Sameh S Elhady, Alaa Sirwi, Hanan Samir, Elsayed A Ibrahim, Ama Kyeraa Thomford, Alaa El Gindy, Ghada M Hadad, Jihan M Badr, Mohamed S Nafie
Thonningia sanguinea Extract: Antioxidant and Cytotoxic Activities Supported by Chemical Composition and Molecular Docking Simulations. Plants (Basel, Switzerland) 10 (10) (2021)
Mohamed S Nafie, Noha M Awad, Hend M Tag, Ibrahim M Abd El-Salam, Mohamed K Diab, Sahar A El-Shatoury
Micromonospora species from rarely-exploited Egyptian habitats: chemical profile, antimicrobial, and antitumor activities through antioxidant property. Applied microbiology and biotechnology 105 (6) (2021)
Enas E Eltamany, Sameh S Elhady, Mohamed S Nafie, Haidy A Ahmed, Dina M Abo-Elmatty, Safwat A Ahmed, Jihan M Badr, Asmaa R Abdel-Hamed
The Antioxidant Carrichtera annua DC. Ethanolic Extract Counteracts Cisplatin Triggered Hepatic and Renal Toxicities. Antioxidants (Basel, Switzerland) 10 (6) (2021)
Mohamed S Nafie, Safaa M Kishk, Sebaey Mahgoub, Atef M Amer
Quinoline-based thiazolidinone derivatives as potent cytotoxic and apoptosis-inducing agents through EGFR inhibition. Chemical biology & drug design (2021)
Reda F A Abdelhameed, Eman S Habib, Ahmed K Ibrahim, Koji Yamada, Maged S Abdel-Kader, Amany K Ibrahim, Safwat A Ahmed, Jihan M Badr, Mohamed S Nafie
Chemical profiling, cytotoxic activities through apoptosis induction in MCF-7 cells and molecular docking of Phyllostachys heterocycla bark nonpolar extract. Journal of biomolecular structure & dynamics (2021)
Noha M Abd El-Fadeal, Mohamed S Nafie, Mohamed K El-Kherbetawy, Amr El-Mistekawy, Hala M F Mohammad, Alaaeldeen M Elbahaie, Abdullah A Hashish, Suliman Yousef AlOmar, Sheka Yagub Aloyouni, Mohamed El-Dosoky, Khaled M Morsy, Sawsan A Zaitone
Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition. International journal of molecular sciences 22 (10) (2021)
Mohamed M Tawfik, Bassant Galal, Mohamed S Nafie, Mona M El Bous, Magdy I El-Bana
Cytotoxic, apoptotic activities and chemical profiling of dimorphic forms of Egyptian halophyte Cakile maritima scop. Journal of biomolecular structure & dynamics (2021)
Reda F A Abdelhameed, Eman S Habib, Ahmed K Ibrahim, Koji Yamada, Maged S Abdel-Kader, Safwat A Ahmed, Amany K Ibrahim, Jihan M Badr, Mohamed S Nafie
Chemical Constituent Profiling of Phyllostachys heterocycla var. Pubescens with Selective Cytotoxic Polar Fraction through EGFR Inhibition in HepG2 Cells. Molecules (Basel, Switzerland) 26 (4) (2021)
Mohamed S Nafie, Ahmed I Khodair, Hebat Allah Y Hassan, Noha M Abd El-Fadeal, Hanin A Bogari, Sameh S Elhady, Safwat A Ahmed
Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches. Molecules (Basel, Switzerland) 27 (1) (2021)
Marwa S Goda, Mohamed S Nafie, Basma M Awad, Maged S Abdel-Kader, Amany K Ibrahim, Jihan M Badr, Enas E Eltamany
In Vitro and In Vivo Studies of Anti-Lung Cancer Activity of Artemesia judaica L. Crude Extract Combined with LC-MS/MS Metabolic Profiling, Docking Simulation and HPLC-DAD Quantification. Antioxidants (Basel, Switzerland) 11 (1) (2021)
Sameh S Elhady, Reda F A Abdelhameed, Mayada M El-Ayouty, Amany K Ibrahim, Eman S Habib, Mohamed Saleh Elgawish, Hashim A Hassanean, Martin K Safo, Mohamed S Nafie, Safwat A Ahmed
New Antiproliferative Triflavanone from Thymelaea hirsuta-Isolation, Structure Elucidation and Molecular Docking Studies. Molecules (Basel, Switzerland) 26 (3) (2021)
Mohamed S Nafie, Sebaey Mahgoub, Atef M Amer
Antimicrobial and antiproliferative activities of novel synthesized 6-(quinolin-2-ylthio) pyridine derivatives with molecular docking study as multi-targeted JAK2/STAT3 inhibitors. Chemical biology & drug design 97 (3) (2020)
Enas E Eltamany, Sameh S Elhady, Haidy A Ahmed, Jihan M Badr, Ahmad O Noor, Safwat A Ahmed, Mohamed S Nafie
Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of Carrichtera annua DC. (Cruciferae). Antioxidants (Basel, Switzerland) 9 (12) (2020)
Ahmed A M Sarhan, Ahmed T A Boraei, Assem Barakat, Mohamed S Nafie
Discovery of hydrazide-based pyridazino[4,5- b ]indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitor for breast cancer therapy. RSC advances 10 (33) (2020)
Safaa M Kishk, Rania M Kishk, Asmaa S A Yassen, Mohamed S Nafie, Nader A Nemr, Gamal Elmasry, Salim Al-Rejaie, Claire Simons
Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies. Molecules (Basel, Switzerland) 25 (21) (2020)
Reda F A Abdelhameed, Mohamed S Nafie, Ahmed K Ibrahim, Koji Yamada, Maged S Abdel-Kader, Amany K Ibrahim, Safwat A Ahmed, Jihan M Badr, Eman S Habib
Cytotoxic, Apoptosis-Inducing Activities, and Molecular Docking of a New Sterol from Bamboo Shoot Skin Phyllostachys heterocycla var. pubescens. Molecules (Basel, Switzerland) 25 (23) (2020)
Enas E Eltamany, Mohamed S Nafie, Dina M Khodeer, Aya H H El-Tanahy, Maged S Abdel-Kader, Jihan M Badr, Reda F A Abdelhameed
Rubia tinctorum root extracts: chemical profile and management of type II diabetes mellitus. RSC advances 10 (41) (2020)
Ranza Elrayess, Mohamed Saleh Elgawish, Marwa Elewa, Mohamed S Nafie, Sameh S Elhady, Asmaa S A Yassen
Synthesis, 3D-QSAR, and Molecular Modeling Studies of Triazole Bearing Compounds as a Promising Scaffold for Cyclooxygenase-2 Inhibition. Pharmaceuticals (Basel, Switzerland) 13 (11) (2020)

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Mohamed S Nafie