PRAME expression in 155 cases of metastatic melanoma.
Sarah E GradeckiCraig L SlingluffAlejandro A GruPublished in: Journal of cutaneous pathology (2020)
A high level of PRAME immunoreactivity was identified in this cohort of metastatic melanoma. Lymph node metastases showed more focal or absent PRAME expression as compared to metastases to other sites. Overall, PRAME is a useful tool for confirming the diagnosis of melanoma in a metastatic setting, in both nodal and visceral deposits.