Predictors and Dynamics of the Humoral and Cellular Immune Response to SARS-CoV-2 mRNA Vaccines in Hemodialysis Patients: A Multicenter Observational Study.

Jens Tomas Van Praet Marijke ReyndersDirk De BacquerLiesbeth Viaene Melanie K Schoutteten Rogier Caluwé Peter Doubel Line HeylenAnnelies V De BelBruno Van Vlem Deborah Steensels An S De Vriese

Published in: Journal of the American Society of Nephrology : JASN (2021)

The mRNA-1273 vaccine's greater immunogenicity may be related to its higher mRNA dose. This suggests a high-dose vaccine might improve the impaired immune response to SARS-CoV-2 vaccination in patients on hemodialysis.

Keyphrases

low dose
immune response
high dose
sars cov
end stage renal disease
chronic kidney disease
peritoneal dialysis
respiratory syndrome coronavirus
newly diagnosed
ejection fraction
binding protein
toll like receptor
prognostic factors
clinical trial
cross sectional