Login / Signup

MRI-based radiomics for prognosis of pediatric diffuse intrinsic pontine glioma: an international study.

Lydia T TamKristen W YeomJason N WrightAlok JajuAlireza RadmaneshMichelle HanSebastian M ToescuMaryam MalekiEric ChenAndrew CampionHollie A LaiAzam A EghbalOzgur OztekinKshitij MankadDarren HargraveThomas S JacquesRobert GoettiRobert M LoberSamuel H CheshierSandy NapelMourad SaidKristian AquilinaChang Y HoMichelle MonjeNicholas A VitanzaSarah A Mattonen
Published in: Neuro-oncology advances (2021)
In this international study, we demonstrate the use of radiomic signatures to create a machine learning model for DIPG prognostication. Standardized, quantitative approaches that objectively measure DIPG changes, including computational MRI evaluation, could offer new approaches to assessing tumor phenotype and serve a future role for optimizing clinical trial eligibility and tumor surveillance.
Keyphrases