Lipid Metabolism, Abdominal Adiposity, and Cerebral Health in the Amish.
Meghann C RyanPeter V KochunovLaura M RowlandBraxton D MitchellS Andrea WijtenburgEls FieremansJelle VeraartDmitry S NovikovXiaoming DuBhim AdhikariFeven FissehaHeather BruceJoshua ChiappelliHemalatha SampathSeth AmentJeffrey O'ConnellAlan R ShuldinerL Elliot HongPublished in: Obesity (Silver Spring, Md.) (2017)
Peripheral lipid/fat indicators were significantly and negatively associated with cerebral WM rather than with GM, independent of age and BP level. Dissecting the fat/lipid components contributing to different brain imaging parameters may open a new understanding of the body-brain connection through lipid metabolism.
Keyphrases
- fatty acid
- cerebral ischemia
- subarachnoid hemorrhage
- resting state
- adipose tissue
- white matter
- healthcare
- public health
- functional connectivity
- high resolution
- mental health
- minimally invasive
- brain injury
- insulin resistance
- health information
- weight gain
- mass spectrometry
- cerebral blood flow
- physical activity
- social media
- fluorescence imaging
- climate change
- photodynamic therapy