Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study.
Letemichael Negash WelekidanEystein SkjerveTsehaye Asmelash DejeneMengistu Welday GebremichaelOla BrynildsrudAngelika AgdesteinGirum Tadesse TessemaTone TønjumSolomon Abebe YimerPublished in: PloS one (2020)
The magnitude of MDR-TB observed among new and previously treated patients is very alarming, which calls for an urgent need for intervention. The high proportion of MDR-TB among newly diagnosed cases indicates ongoing transmission, which suggests the need for enhanced TB control program performance to interrupt transmission. The increased proportion of MDR-TB among previously treated cases indicates a need for better patient management to prevent the evolution of drug resistance. Assessing the TB control program performance gaps and an optimal implementation of the WHO recommended priority actions for the management of drug-resistant TB, is imperative to help reduce the current high MDR-TB burden in the study region.
Keyphrases
- multidrug resistant
- newly diagnosed
- drug resistant
- mycobacterium tuberculosis
- end stage renal disease
- acinetobacter baumannii
- gram negative
- ejection fraction
- chronic kidney disease
- randomized controlled trial
- quality improvement
- healthcare
- prognostic factors
- pulmonary tuberculosis
- klebsiella pneumoniae
- risk factors
- peritoneal dialysis
- escherichia coli
- physical activity
- emergency department
- patient reported