The effects of probiotic and synbiotic supplementation on inflammation, oxidative stress, and circulating adiponectin and leptin concentration in subjects with prediabetes and type 2 diabetes mellitus: a GRADE-assessed systematic review, meta-analysis, and meta-regression of randomized clinical trials.

Kaveh NaseriSaeede SaadatiFarahnaz GhaemiDamoon Ashtary-LarkyOmid AsbaghiAmir SadeghiReza AfrishamBarbora De Courten

Published in: European journal of nutrition (2022)

A consumption of probiotics or synbiotics could be a useful intervention to improve cardiometabolic outcomes through a reduced inflammation and oxidative stress in patients with prediabetes and T2DM.

Keyphrases

oxidative stress
systematic review
meta analyses
diabetic rats
dna damage
glycemic control
randomized controlled trial
ischemia reperfusion injury
induced apoptosis
metabolic syndrome
type diabetes
insulin resistance
clinical trial
heat shock
cardiovascular disease
signaling pathway
skeletal muscle
double blind