Metabolic impairments associated with type 2 diabetes mellitus and the potential effects of exercise therapy: An exploratory randomized trial based on untargeted metabolomics.
Furong ZhangXixi ChenMingxiao YangXiaoyu ShenYiliang WangDongling ZhongFang ZengRongjiang JinPublished in: PloS one (2024)
T2DM patients displayed impaired carbohydrate, lipid, and amino acid metabolism, and exercise therapy improved their metabolic health. Different modalities may act through different pathways. Tai Chi may improve disrupted BCAAs metabolism, whereas brisk walking mainly regulates steroid hormone biosynthesis and arachidonic acid metabolism.
Keyphrases
- high intensity
- mass spectrometry
- amino acid
- end stage renal disease
- healthcare
- ejection fraction
- newly diagnosed
- physical activity
- public health
- resistance training
- mental health
- glycemic control
- stem cells
- type diabetes
- human health
- body composition
- health information
- metabolic syndrome
- risk assessment
- fatty acid
- social media
- mesenchymal stem cells
- cardiovascular risk factors
- patient reported outcomes
- insulin resistance
- cell wall