Ethical Challenges Associated with Pathogen and Host Genetics in Infectious Disease.
Richard MilneChristine PatchPublished in: The New bioethics : a multidisciplinary journal of biotechnology and the body (2022)
The Covid-19 pandemic has demonstrated the potential of genomic technologies for the detection and surveillance of infectious diseases. Pathogen genomics is likely to play a major role in the future of research and clinical implementation of genomic technologies. However, unlike human genetics, the specific ethical and social challenges associated with the implementation of infectious disease genomics has received comparatively little attention. In this paper, we contribute to this literature, focusing on the potential consequences for individuals and communities of the use of these technologies. We concentrate on areas of challenges related to privacy, stigma, discrimination and the return of results in the cases of the surveillance of known pathogens, metagenomics and host genomics.
Keyphrases
- infectious diseases
- healthcare
- single cell
- primary care
- public health
- mental health
- endothelial cells
- systematic review
- copy number
- candida albicans
- quality improvement
- decision making
- human health
- working memory
- health information
- risk assessment
- social support
- label free
- dna methylation
- genome wide
- human immunodeficiency virus
- climate change
- loop mediated isothermal amplification
- multidrug resistant
- hepatitis c virus
- social media
- real time pcr
- hiv infected
- quantum dots
- sensitive detection
- antiretroviral therapy