The effects of external Mn2+ concentration on hyphal morphology and citric acid production are mediated primarily by the NRAMP-family transporter DmtA in Aspergillus niger.
Balázs FejesJean-Paul OuedraogoErzsébet FeketeErzsébet SándorMichel FlipphiÁron SoósÁkos P MolnárBéla KovácsChristian P KubicekAdrian TsangLevente KaraffaPublished in: Microbial cell factories (2020)
Our results demonstrate that dmtA is physiologically important in the transport of Mn2+ ions in A. niger, and manipulation of its expression modulates citric acid overflow.