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Patterns of response and drugs involved in hypersensitivity reactions to beta-lactams in children.

Isabel Torres-RojasDiana Pérez-AlzateMaria Luisa SomozaElisa Haroun DiazFrancisco Javier RuanoAna Prieto-Moreno PfeiferTeodorikez-Wilfox Jimenez-RodriguezJavier Fernandez SánchezMiguel BlancaGabriela Canto DiezNatalia Blanca-López
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)
There were few confirmed cases of either type of reaction. Skin testing proved less valuable in non-immediate reactions, over half of which would also have been lost in a short DPT protocol. Selective responders to amoxicillin were more likely to have non-immediate reactions, while clavulanic acid selectivity was exclusive to the non-immediate typology. Over half the cases with DPTs required 6-7 days of treatment for DHR confirmation.
Keyphrases
  • randomized controlled trial
  • young adults
  • drug induced
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