Cognitive functioning following brain irradiation as part of cancer treatment: Characterizing better cognitive performance.

Shan S WongL Douglas CaseNancy E AvisTiffany L CummingsChristina K CramerStephen R Rapp

Published in: Psycho-oncology (2019)

There is a subgroup of survivors with minimal long-term cognitive deficits despite undergoing a full course of brain RT as part of cancer treatment. Lower fatigue had the strongest association with better cognitive performance. Interventions targeting cancer-related fatigue may help buffer the neurotoxic effects of brain RT.

Keyphrases

resting state
white matter
functional connectivity
cerebral ischemia
physical activity
sleep quality
young adults
clinical trial
randomized controlled trial
multiple sclerosis
drug delivery
radiation therapy
depressive symptoms
blood brain barrier
open label
double blind