A critical role for c-Myc in group 2 innate lymphoid cell activation.
Longyun YeJiexue PanMingwei LiangMuhammad Asghar PashaXiaofei ShenShanti S D'SouzaIvan Ting Hin FungYinna WangGargi PatelDale D TangQi YangPublished in: Allergy (2020)
c-Myc expression is upregulated during ILC2 activation. c-Myc is essential for ILC2 activation and their in vivo pathogenic effects. These findings suggest that targeting c-Myc may unlock novel strategies to combat asthma or asthma exacerbation.