Overexpression of MicroRNA-148b-3p stimulates osteogenesis of human bone marrow-derived mesenchymal stem cells: the role of MicroRNA-148b-3p in osteogenesis.

Samaneh MollazadehBibi Sedigheh Fazly BazzazVajiheh NeshatiAntoine A F de VriesHojjat Naderi-MeshkinMajid MojaradMahdi MirahmadiZeinab NeshatiMohammad Amin Kerachian

Published in: BMC medical genetics (2019)

Since lentivirally overexpressed miR-148b-3p increased osteogenic differentiation capability of BM-MSCs, this miR could be applied as a therapeutic modulator to optimize bone function.

Keyphrases

bone marrow
mesenchymal stem cells
cell proliferation
bone regeneration
umbilical cord
endothelial cells
long non coding rna
bone mineral density
induced pluripotent stem cells
pluripotent stem cells
soft tissue