Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.
Xianyong YinKwangwoo KimHiroyuki SuetsuguSo-Young BangLeilei WenMasaru KoidoEunji HaLu LiuYuma SakamotoSungsin JoRui-Xue LengNao OtomoViktoryia LaurynenkaYoung-Chang KwonYujun ShengNobuhiko SuganoMi Yeong HwangWeiran LiMasaya MukaiKyungheon YoonMinglong CaiKazuyoshi IshigakiWon Tae ChungHe HuangDaisuke TakahashiShin-Seok LeeMengwei WangKohei KarinoSeung-Cheol ShimXiaodong ZhengTomoya MiyamuraYoung Mo KangDong-Qing YeJunichi NakamuraChang-Hee SuhYuanjia TangGoro MotomuraYong-Beom ParkHuihua DingTakeshi KurodaJung-Yoon ChoeChengxu LiHiroaki NiiroYoungho ParkChangbing ShenTakeshi MiyamotoGa-Young AhnWenmin FeiTsutomu TakeuchiJung-Min ShinKeke LiYasushi KawaguchiYeon-Kyung LeeYong-Fei WangKoichi AmanoDae Jin ParkWanling YangYoshifumi TadaKen YamajiMasato ShimizuTakashi AtsumiAkari SuzukiTakayuki SumidaYukinori OkadaKoichi MatsudaKeitaro MatsuoYuta Kochinull nullLeah C KottyanMatthew T WeirauchSreeja ParameswaranShruti EswarHanan SalimXiaoting ChenKazuhiko YamamotoJohn B HarleyKoichiro OhmuraTae Hwan KimSen YangTakuaki YamamotoBong-Jo KimNan ShenShiro IkegawaHye-Soon LeeXuejun ZhangChikashi C TeraoYong CuiSang-Cheol BaePublished in: Annals of the rheumatic diseases (2020)
This study reiterates the power of large-scale genome-wide meta-analysis for novel genetic discovery. These findings shed light on genetic and biological understandings of SLE.