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Mesenchymal stem cells transplanted into spinal cord injury adopt immune cell-like characteristics.

Ramil HakimRuxandra CovacuVasilios ZachariadisArvid FrostellSreenivasa Raghavan SankavaramLou BrundinMikael Svensson
Published in: Stem cell research & therapy (2019)
MSCs transplanted into SCI upregulate expression of CD45 and MHC-II and expression of genes related to cytokine production, phagocytosis/endocytosis, and immune cells/response and thereby adopt immune cell-like characteristics within the recipient.
Keyphrases
  • spinal cord injury
  • mesenchymal stem cells
  • poor prognosis
  • umbilical cord
  • spinal cord
  • bone marrow
  • neuropathic pain
  • genome wide
  • binding protein
  • long non coding rna
  • cell therapy
  • gene expression
  • dna methylation