Is quality of life a suitable measure of patient decision aid effectiveness? Sub-analysis of a Cochrane systematic review.
Claudia RutherfordMadeleine T KingPhyllis ButowFrance LegareAnne LyddiattIntissar SouliOrlando RinconesDawn StaceyPublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2018)
PtDAs did not conclusively impact HRQOL. If this holds generally, then HRQOL is an uninformative endpoint for PtDA effectiveness trials. When planning trials of PtDAs, investigators considering HRQOL endpoints should consider whether and why their PtDA is likely to affect HRQOL in their context, and if so, which specific aspect(s) of HRQOL and at which time-point(s), and ensure HRQOL is assessed accordingly.