Immunohistochemical expression of TFIIH and XPF in oral tongue squamous cell carcinoma.

Melka Coêlho SáThalita Santana ConceiçãoEdilmar de Moura SantosEverton Freitas de MoraisHébel Cavalcanti GalvãoRoseana de Almeida Freitas

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2019)

We have demonstrated that the overexpression of TFIIH correlates positively with node metastasis, while XPF correlates negatively with node metastasis; therefore, the expression of XPF and TFIIH had a potential value for predicting the progression of OTSCC patients.

Keyphrases

squamous cell carcinoma
poor prognosis
end stage renal disease
lymph node
ejection fraction
newly diagnosed
chronic kidney disease
cell proliferation
binding protein
prognostic factors
climate change
locally advanced