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GuideMaker: Software to design CRISPR-Cas guide RNA pools in non-model genomes.

Ravin PoudelLidimarie Trujillo RodriguezChristopher R ReischAdam R Rivers
Published in: GigaScience (2022)
GuideMaker enables the rapid design of genome-wide gRNA for any CRISPR-Cas enzyme in non-model organisms. While GuideMaker is designed with prokaryotic genomes in mind, it can efficiently process eukaryotic genomes as well. GuideMaker is available as command-line software, a stand-alone web application, and a tool in the CyCverse Discovery Environment. All versions are available under a Creative Commons CC0 1.0 Universal Public Domain Dedication.
Keyphrases
  • sensitive detection
  • crispr cas
  • genome editing
  • genome wide
  • healthcare
  • dna methylation
  • small molecule
  • data analysis
  • emergency department
  • gene expression
  • gram negative
  • multidrug resistant
  • nucleic acid
  • single cell