Lysophosphatidic acid supports the development of vitrified ovarian follicles by decreasing the incidence of cell death: An experimental study.

Neda AbedpourNassim GhorbanmehrMojdeh Salehnia

Published in: International journal of reproductive biomedicine (2022)

LPA improved the survival and developmental potential of the isolated follicles. Despite some alterations in the expression of apoptosis-related genes in the vitrified ovaries, LPA had positive effects on the survival and development of these follicles.

Keyphrases

cell death
cell cycle arrest
poor prognosis
oxidative stress
free survival
endoplasmic reticulum stress
binding protein
human health
signaling pathway
climate change
pi k akt