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Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway.

Xing ZhangSen WangHaixiao WangJiacheng CaoXiaoxu HuangZheng ChenPenghui XuGuangli SunJianghao XuJialun LvZe-Kuan Xu
Published in: Molecular cancer (2019)
We proved that circNRIP1 sponges miR-149-5p to affect the expression level of AKT1 and eventually acts as a tumour promotor in GC.
Keyphrases
  • cell proliferation
  • signaling pathway
  • poor prognosis
  • binding protein
  • long non coding rna
  • mass spectrometry
  • high resolution
  • liquid chromatography
  • simultaneous determination