Two new JK silencing alleles identified by single molecule sequencing with 20-Kb long-reads.

Kazumi IsaShinnosuke TakadaHiromi TakedaHatsue TsuneyamaKenichi OgasawaraDaisuke TakahashiToru MiyazakiShigeki MiyataMasahiro Satake

Published in: Transfusion (2023)

We identified new JK silencing alleles and their critical SNVs by single-molecule sequencing and the findings were confirmed by transfection and expression studies.

Keyphrases

single molecule
single cell
atomic force microscopy
poor prognosis
living cells
case control
high resolution