Women's contributions to radiobiology in Ireland; from small beginnings….
Orla HoweFiona M LyngCarmel MothersillPublished in: International journal of radiation biology (2021)
Over the last 45 years, the women of the Radiation and Environmental Science Centre (RESC) contributed to the major paradigm shift in low dose radiobiology contributing exciting new research concerning non-targeted effects, including discovery of lethal mutations, medium transfer bystander mechanisms, and signaling pathways. They also developed translational research using human explant culture systems with unique immunocytochemical methods and more recently evolved to molecular and spectroscopic analysis of clinical samples. The RESC also developed unique in vitro research methods into effects of radiation on non-human species of concern in ecosystems.
Keyphrases
- endothelial cells
- low dose
- polycystic ovary syndrome
- induced pluripotent stem cells
- signaling pathway
- pluripotent stem cells
- public health
- small molecule
- climate change
- pregnancy outcomes
- drug delivery
- metabolic syndrome
- high throughput
- insulin resistance
- epithelial mesenchymal transition
- adipose tissue
- human health
- single molecule
- induced apoptosis