MicroRNA expression profiling of cutaneous squamous cell carcinomas and precursor lesions.
Akbor HossainLisa N TomAla Melati-RadMiko YamadaSabrina HammerlindlKasturee JagirdarTarl W ProwHans Peter SoyerMitchell S StarkPublished in: Skin health and disease (2024)
This study confirmed the continuum of AK with IEC and SCC highlighting that miRNA expression plays a role in keratinocyte transformation. Development of our putative miRNA biomarker candidates is warranted to aid in clinical management of patients experiencing high AK load to determine the most appropriate treatment.