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MicroRNA expression profiling of cutaneous squamous cell carcinomas and precursor lesions.

Akbor HossainLisa N TomAla Melati-RadMiko YamadaSabrina HammerlindlKasturee JagirdarTarl W ProwHans Peter SoyerMitchell S Stark
Published in: Skin health and disease (2024)
This study confirmed the continuum of AK with IEC and SCC highlighting that miRNA expression plays a role in keratinocyte transformation. Development of our putative miRNA biomarker candidates is warranted to aid in clinical management of patients experiencing high AK load to determine the most appropriate treatment.
Keyphrases
  • squamous cell
  • poor prognosis
  • genome wide
  • high grade
  • gene expression
  • combination therapy
  • long non coding rna
  • replacement therapy