PINOT: an intuitive resource for integrating protein-protein interactions.
James E TomkinsRaffaele FerrariNikoleta VavourakiJohn HardyRuth C LoveringPatrick A LewisLiam J McGuffinClaudia ManzoniPublished in: Cell communication and signaling : CCS (2020)
PINOT is a tool that allows users to survey the curated literature, extracting PPI data in relation to a list of proteins of interest. PINOT extracts a similar numbers of PPIs as other, analogous, tools and incorporates a set of innovative features. PINOT is able to process large queries, it downloads human PPIs live through PSICQUIC and it applies quality control filters on the downloaded PPI data (i.e. removing the need for manual inspection by the user). PINOT provides the user with information on detection methods and publication history for each downloaded interaction data entry and outputs the results in a table format that can be straightforwardly further customised and/or directly uploaded into network visualization software. Video abstract.