Diffuse large B-cell lymphoma in Southeast Asian cohort: expression patterns of B-cell receptor (BCR) repertoire and its linkage with molecular subtypes and response to R-CHOP therapy.
Noraidah MasirAriz AkhterTariq M RoshanChandramaya Sabrina FlorenceFaridah Abdul-RahmanNor Rafeah TumianPhang Kean-ChangGhaleb ElyamanyMeer-Taher Shabani-RadAdnan MansoorPublished in: Journal of clinical pathology (2019)
Our data provide a clear association between high BCR activity in DLBCL and response to therapy in a distinct population. Molecular data provided here will pave the pathway for the provision of promising novel-targeted therapies to patients with DLBCL in Southeast Asia.
Keyphrases
- diffuse large b cell lymphoma
- epstein barr virus
- acute lymphoblastic leukemia
- electronic health record
- tyrosine kinase
- big data
- poor prognosis
- chronic myeloid leukemia
- binding protein
- stem cells
- single molecule
- gene expression
- machine learning
- genome wide
- hepatitis c virus
- data analysis
- mesenchymal stem cells
- hiv testing
- smoking cessation
- antiretroviral therapy