Bone mineral density in egyptian children with juvenile idiopathic arthritis: possible correlation to serum RANKL / osteoprotegerin (OPG) ratio and OPG gene polymorphisms.
Riham EidMaha AbdelsalamAya Ahmed FathyHadil M AboleneinEman Bakr ElmarghanyAya Ahmed El-HanafyNashwa HamdyDina Salama Abd-ElmagidNermeen A NiazyDina M Abd-El GhaffarPublished in: Pediatric rheumatology online journal (2023)
Egyptian children with JIA have decreased BMD. rs2073617 TT genotype and T allele, RANKL/OPG ratio are possible determinants of reduced BMD in JIA. Our results underline the importance of frequent monitoring of BMD in JIA children and trying to control disease activity to preserve long term bone health.
Keyphrases
- juvenile idiopathic arthritis
- disease activity
- bone mineral density
- rheumatoid arthritis
- young adults
- systemic lupus erythematosus
- postmenopausal women
- rheumatoid arthritis patients
- body composition
- healthcare
- ankylosing spondylitis
- public health
- nuclear factor
- immune response
- mental health
- toll like receptor
- social media
- soft tissue