Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells.

Juan A Santamaria-BarriaShan ZengJonathan B GreerMichael J BeckmanAdrian M SeifertNoah A CohenJennifer Q ZhangMegan H CrawleyBenjamin L GreenJennifer K LooJoanna H MaltbaekRonald P DeMatteo

Published in: PloS one (2019)

F4/80hi KCs are Mer+ and can be subdivided based on Csf1r expression. Csf1r or Mer inhibition each reduces KC cytokine production and delays LR.

Keyphrases

induced apoptosis
poor prognosis
stem cells
cell cycle arrest
cerebrospinal fluid
cell proliferation
cell death
binding protein
endoplasmic reticulum stress